Argentina's Lionel Messi and Brazil's Vinicius Júnior had frustrating nights in South American World Cup qualifying. While Messi could not help his team avoid a 2-1 defeat at Paraguay, Vinicius Junior missed a second-half penalty as Brazil was held to a 1-1 draw at Venezuela on Thursday.

Lionel Messi returns to action with the Argentine national team Thursday night for a 2026 World Cup qualifying match on the road against Paraguay.

World champions Argentina suffered a 2-1 defeat to Paraguay while rivals Brazil were held to a 1-1 draw at Venezuela as South America's big guns struggled in CONMEBOL World Cup qualifying on Thursday.

Argentina are set to face Peru this Tuesday in the South American qualifiers for the 2026 World Cup, but Lionel Messi's team has suffered a significant setback. Two key players have been ruled out due to injury concerns.

Paraguay shocked Argentina 2-1 at Estadio Defensores del Chaco in a riveting FIFA World Cup qualifier. Lautaro Martínez started Argentina's score in the 11th minute; then, in the 19th minute, Paraguayan Antonio Sanabria equalised with an amazing bicycle kick.